Product Overview
[Drug Name]
Generic Name: Theophylline Sustained-Release Tablets
Trade Name: Aqi Cha Jian Huan Shi Sustained-Release Tablets 0.1g*36 Tablets
Pinyin Code: AQi Cha Jian Huan Shi Tablets 0.1g*36 Tablets
[Main Ingredients]
The main ingredient of this product is theophylline, chemically named: 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione-hydrate Molecular Formula: (C7H8N4O2).H2O Molecular Weight: 198.18
[Properties]
This product is a white tablet.
[Indications/Main Functions]
Indicated for the relief of wheezing symptoms in conditions such as bronchial asthma, asthmatic bronchitis, and obstructive pulmonary emphysema; it can also be used for wheezing associated with heart failure.
[Specifications]
0.1g*36 tablets
[Dosage and Administration]
Oral administration. Do not crush or chew. For adults and children over 12 years old, the starting dose is 0.1g-0.2g (1-2 tablets) twice daily with 100ml of warm water in the morning and evening. The dosage can be adjusted based on the patient's condition and efficacy, but the daily dose should not exceed 0.9g (9 tablets) in two divided doses.
[Adverse Reactions]
Theophylline toxicity typically occurs at serum concentrations of 15-20μg/ml, especially at the beginning of treatment. Early symptoms include nausea, vomiting, irritability, and insomnia. When serum concentrations exceed 20μg/ml, tachycardia and arrhythmias may occur. When serum theophylline concentrations exceed 40μg/ml, fever, dehydration, and convulsions may occur. In severe cases, respiratory and cardiac arrest may lead to death.
[Contraindications]
This product is contraindicated in patients with allergies, active peptic ulcers, and uncontrolled convulsive disorders.
[Precautions]
1. As with other theophylline sustained-release preparations, this product is not suitable for patients with status asthmaticus or acute bronchospasm.
2. Serum theophylline concentration should be monitored regularly to ensure maximum therapeutic effect without the risk of excessive blood concentration.
3. Patients with renal or hepatic insufficiency, patients over 55 years old, especially men, and patients with chronic lung disease, patients with heart failure caused by any reason, and patients with persistent fever. Patients using certain medications and those with reduced theophylline clearance often have significantly prolonged maintenance of serum theophylline concentration after discontinuation of concomitant medications. The dosage should be adjusted or the medication interval should be extended as appropriate.
4. Theophylline preparations can cause arrhythmias and/or worsen existing arrhythmias; any changes in the patient's heart rate and/or rhythm should be monitored and studied.
5. This product should be used with caution in patients with hypoxemia, hypertension, or a history of peptic ulcers.
