Product Overview
[Drug Name]
Generic Name: Cefaclor and Bromhexine Hydrochloride Tablets
Trade Name: Zhengdasuke
English Name: Cefaclor and Bromhexine Hydrochloride Tablets
Chinese Pinyin: Keluojixin pian
[Ingredients]
This product is a combination preparation. Each tablet contains 500mg of cefaclor and 16mg of bromhexine.
[Properties]
This product is a film-coated tablet. After removing the coating, it appears white or light yellow.
[Indications]
This product is suitable for the treatment of patients with respiratory tract infections caused by susceptible bacteria and accompanied by thick, difficult-to-expel sputum.
[Dosage and Administration]
Oral. Adults: Generally, one tablet three times daily. The duration of treatment will be determined by your doctor.
[Adverse Reactions]
Possible side effects include gastrointestinal symptoms, including diarrhea, nausea, dizziness, abdominal pain, and vomiting. Long-term use of cephalosporins may lead to the proliferation of nonsusceptible bacteria, resulting in gastrointestinal symptoms such as diarrhea and pseudomembranous colitis. In rare cases, temporary liver discomfort or cholestatic jaundice may occur. Lymphadenopathy and proteinuria may also occur. These symptoms resolve spontaneously within a few days after discontinuation of the drug. Allergic symptoms include skin rash, itching, flushing, dyspnea, and fever with chills. Erythematous exudates, exfoliative dermatitis, and Stephens-Johnson syndrome may occasionally occur after taking cephalosporins. Other symptoms include weakness, edema, dyspnea, temporary loss of consciousness, and a rapid heart rate. In such cases, the drug should be discontinued and medical attention sought. Neurological conditions: Temporary excitement, restlessness, insomnia, confusion, increased muscle tone, dizziness, and drowsiness may rarely occur. Laboratory changes after taking cefaclor include mild elevations in liver SGOT, SGPT, and alkaline phosphatase. Temporary leukopenia, transient lymphocytosis, and rarely, hemolytic anemia may also occur. Rarely, thrombocytopenia, reversible interstitial nephritis, genital pruritus, and vaginitis may occur.
[Contraindications]
This product is contraindicated in patients allergic to cephalosporins or bromhexine.
[Precautions]
1. This product has a cross-allergic reaction with penicillins or cephamycin. Therefore, it should be used with caution in patients allergic to penicillins, penicillin derivatives, penicillamine, and cephamycin. 2. Use with caution in patients with impaired renal or hepatic function. 3. Use with caution in patients with a history of gastrointestinal diseases, especially those with ulcerative colitis, regional enteritis, or antibiotic-associated colitis. 4. Long-term use of this product may cause dysbiosis and secondary infection. Please read the package insert carefully and use as directed by your doctor.
[Use in Special Populations]
Precautions for children: Not yet available.
Precautions for pregnancy and lactation: Not yet available.
Precautions for the elderly: Not yet available.
[Drug Interactions]
Drug interactions may occur if used concurrently with other medications. Please consult your doctor or pharmacist for details.
[Pharmacological Actions]
Not yet available.
[Storage]
Store tightly closed and protected from light.
[Specifications]
Each tablet contains 250mg of cefaclor and 8.77mg of bromhexine hydrochloride.
[Packaging Specifications]
12 tablets per box.
[Expiration Date]
24 months
[Approval Number]
National Medicine Standard H20051810
[Manufacturer]
Company Name: Jiangsu Zhengda Qingjiang Pharmaceutical Co., Ltd.
