Product Overview
[Drug Name]
Generic Name: Amlodipine Besylate Tablets
Trade Name: De En De Amlodipine Besylate Tablets 5mg*28 Tablets
Pinyin Code: DeEnDe BenHuangSuanAnLvDiPingPian 5mg*7Pian*4Ban
[Main Ingredient]
Amlodipine Besylate
[Appearance]
This product is a white tablet.
[Indications/Main Functions]
1. Essential hypertension, used alone or in combination with other antihypertensive drugs. 2. Chronic stable variant angina, used alone or in combination with other antianginal drugs.
[Precautions]
1. Angina pectoris and/or myocardial infarction. Rare. In patients with severe obstructive coronary artery disease, the frequency, duration, and/or severity of angina attacks may increase, or they may develop into acute myocardial infarction, when starting or increasing the dose of calcium channel antagonists. The mechanism is unknown. 2. Hypotension. Because this drug gradually develops vasodilation, acute hypotension rarely occurs with oral administration. However, caution is advised when using this drug in combination with other peripheral vasodilators, especially in patients with severe aortic valve stenosis. 3. Patients with heart failure. Calcium channel blockers should be used with caution in patients with heart failure. 4. Patients with hepatic impairment. This drug should be used with caution in patients with severe hepatic impairment. 5. Patients with renal failure. The initial dose can remain unchanged in patients with renal failure. 6. Discontinuation of beta-blockers. This drug does not protect against rebound symptoms associated with abrupt discontinuation of beta-blockers. Therefore, a gradual dose reduction is still necessary when discontinuing beta-blockers. 7. This drug can be used safely in patients with obstructive pulmonary disease, well-compensated heart failure, peripheral vascular disease, diabetes, and lipid disorders.
[Drug Interactions]
Contraindicated for patients allergic to dihydropyridine calcium channel blockers
[Specifications]
5mg*7 tablets*4 plates
[Dosage and Administration]
The usual oral starting dose is 5mg, once a day, and the maximum dose is not more than 10mg, once a day. Thin people, weak people, elderly patients or those with impaired liver function start with 2.5mg, once a day; those who take other antihypertensive drugs should also start with this dose. The dosage is adjusted according to individual needs, and the adjustment period should be no less than 7-14 days so that the doctor can fully evaluate the patient's response to the dose. However, under the premise of clinical guarantee, the adjustment speed can be accelerated. The recommended dose for the treatment of angina pectoris is 5-10mg, and the elderly patients or those with impaired liver function need to reduce the dose.(1) The initial dose for the treatment of hypertension and angina pectoris is 2.5mg, once a day; based on the patient's clinical response, the dose can be increased to a maximum of 5mg, once a day. (2) This product does not require dosage adjustment when used in combination with thiazide diuretics, beta-blockers, and angiotensin-converting enzyme inhibitors.
[Adverse Reactions]
See instructions for details.
[Contraindications]
This product is contraindicated in patients who are allergic to dihydropyridine calcium antagonists.
