Product Overview
[Drug Name]
Generic Name: Compound Amiloride Hydrochloride Tablets
Trade Name: Wuduli
English Name: Compound Amiloride Hydrochloride Tablets
Chinese Pinyin: Yansuan Amiluoli Pian
[Ingredients]
Main Ingredients: Amiloride Hydrochloride, Hydrochlorothiazide
[Properties]
This product is an off-white tablet.
[Indications]
It is used for edema and ascites caused by conditions such as hypertension, heart failure, and cirrhosis.
[Dosage and Administration]
Oral administration: 1-2 tablets once daily, or twice daily if necessary, morning and evening, or as directed by a physician. Take with food.
[Adverse Reactions]
Side effects such as dry mouth, nausea, abdominal distension, dizziness, and chest tightness may occur, but discontinuation of the drug is generally not necessary.
[Contraindications]
This product is contraindicated in patients with hyperkalemia or severe renal insufficiency.
[Precautions]
Regular monitoring of blood potassium, sodium, and chloride levels is recommended for long-term use.
[Use in Special Populations]
Precautions for children: Not yet available.
Precautions for pregnancy and lactation: Not yet available.
Precautions for the elderly: Not yet available.
[Drug Interactions]
Do not use with other potassium-sparing diuretics or potassium salts.
[Pharmacological Actions]
Amiloride is a potassium-sparing diuretic that acts on the distal renal tubule, blocking the sodium-potassium exchange mechanism, promoting sodium and chloride excretion while reducing potassium and hydrogen ion secretion. Its effects are independent of aldosterone, and its own natriuretic and antihypertensive activity is weak. However, it exhibits synergistic effects when used in combination with thiazides (hydrochlorothiazide) or loop diuretics. This combination preparation exhibits synergistic potassium-sparing diuretic and antihypertensive effects. Combining the effects of amiloride and hydrochlorothiazide, it exerts natriuretic and diuretic effects on both the distal and proximal renal tubules. Therefore, this product achieves both potassium sparing and diuretic effects, avoiding the hypokalemic effects of hydrochlorothiazide alone and the weak diuretic potency of amiloride.
[Storage] Store in a dark, airtight container.
[Specification] 24 tablets
[Packaging] Box
[Expiration Period] 24 months
[Approval Number] National Medicine Standard H10900029
[Manufacturer] Jiangsu Desano Pharmaceutical Co., Ltd.
