Product Overview
[Drug Name]
Generic Name: Ursodeoxycholic Acid Tablets
Trade Name: DiFeite Ursodeoxycholic Acid Tablets 50mg*30 Tablets
Pinyin Full Code: DiFeiTe XiongQuYangDanSuanPian 50mg*30 Tablets
[Main Ingredients]
The main ingredient of this product is ursodeoxycholic acid. Its chemical name is 3?,7?-dihydroxy-5?-cholestane-24-oic acid. Structural Formula: C24H4004. Molecular Weight: 392.58
[Properties]
The main ingredient of this product is ursodeoxycholic acid. Its chemical name is 3?,7?-dihydroxy-5?-cholestane-24-oic acid. Structural Formula: Molecular Formula: C24H4004 Molecular Weight: 392.58
[Indications/Main Functions]
This product is used for the treatment of cholesterol gallstones, gallstone formation, and cholestatic steatorrhea. It can also be used to prevent drug-induced gallstone formation and treat steatorrhea (after ileal resection).
[Specifications]
50mg*30 tablets
[Dosage and Administration]
Adults: Oral: 8-10 mg/kg daily, divided into morning and evening doses with meals. The minimum course of treatment is 6 months. If ultrasound and cholecystography show no improvement after 6 months, the drug can be discontinued. If the gallstones are partially dissolved, continue the drug until they are completely dissolved.
[Adverse Reactions]
This product has less toxicity and side effects than chenodeoxycholic acid and generally does not cause diarrhea. Other occasional adverse reactions include constipation, allergies, headache, dizziness, pancreatitis, and tachycardia.
[Contraindications]
This product is contraindicated in patients with allergies, severe hepatitis, ulcer disease, or biliary obstruction.
[Drug Interactions]
Oral contraceptives can increase bile saturation. Other birth control measures should be used during treatment with this drug to avoid compromising efficacy.
[Precautions]
1. Long-term use of this drug may increase the number of peripheral platelets. 2. If recurrent biliary colic occurs during treatment for cholesterol stones, symptoms do not improve or even worsen, or significant stone calcification occurs, treatment should be discontinued and surgery performed. 3. This drug does not dissolve pigment stones, mixed stones, or radiopaque stones.
[Pediatric Use]
This study has not been conducted and no reliable references are available.
[Elderly Use]
Use with caution in elderly patients.
[Pharmacology and Toxicology]
This drug increases bile acid secretion and alters bile acid composition, increasing its content in bile. It also significantly reduces the molar concentration of cholesterol and cholesterol esters and the cholesterol saturation index in human bile, thereby facilitating the gradual dissolution of cholesterol in stones.
