Product Overview
[Drug Name]
Generic Name: Thymosin Enteric-Coated Tablets
Trade Name: Diersu Thymosin Enteric-Coated Tablets 20mg x 10 Tablets
[Main Ingredients]
The main ingredient of this product is thymosin, a biologically active peptide extracted from the thymus of healthy calves.
[Properties]
This product is an enteric-coated tablet. After removing the coating, it appears off-white or light yellow to yellow-brown.
[Indications/Main Functions]
1. For patients with chronic hepatitis B.
2. Various primary or secondary T-cell deficiency diseases.
3. Certain autoimmune diseases.
4. Various diseases with impaired cellular immunity.
5. Adjuvant treatment for tumors. (See package insert for details.)
[Specifications]
20mg x 10 tablets (Diersu)
[Dosage and Administration]
Oral. 20mg (1 tablet) 1-3 times daily, or as directed by a physician.
[Adverse Reactions]
1. Well tolerated. Some patients may experience adverse reactions such as nausea, fever, dizziness, chest tightness, and weakness. A few patients may experience occasional drowsiness.
2. Patients with chronic hepatitis B may experience a transient increase in ALT levels when using this product. If there are no signs of liver failure, this product can continue to be used.
3. A very small number of patients may experience mild allergic reactions, which disappear after discontinuation of the drug.
[Contraindications]
1. This product is contraindicated in patients with allergic reactions to this product or those who have undergone organ transplants.
2. This product is contraindicated in patients with hyperthymic conditions or thymic tumors.
[Drug Interactions]
1. This product can be used in combination with many commonly used medications, including interferon, anti-inflammatory drugs, antibiotics, hormones, analgesics, antihypertensive drugs, diuretics, cardiovascular drugs, central nervous system drugs, and contraceptives, without any interference.
2. This product has a synergistic effect with interferon in improving immune function.
3. This product can enhance its antibacterial effect when used in combination with antibiotics.
4. This product can be used in combination with chemotherapy drugs to reduce the toxic side effects of chemotherapy.
[Precautions]
1. This product exerts its therapeutic effect by enhancing the patient's immune function. Therefore, it should be used with caution in patients receiving immunosuppressive therapy (e.g., organ transplant recipients) unless the benefits clearly outweigh the risks.
2. Liver function should be monitored regularly during treatment.
3. Use with caution in patients under 18 years of age.
[Pediatric Use]
Not yet established.
[Elderly Use]
Not yet established.
[Overdose]
There have been no reports of human overdose (therapeutic or accidental). Animal toxicity studies have shown no adverse reactions at doses below 10 mg/g (the highest dose used in current studies).
[Pharmacology and Toxicology]
This product is an immunomodulatory drug. It regulates and enhances the body's cellular immune function, promoting T cell maturation. It can promote the maturation of T lymphocytes in peripheral blood after mitogen activation, increase the secretion of various lymphokines (such as α- and γ-interferons, interleukin-2, and interleukin-3) by T cells in response to various antigens or mitogens, and increase the levels of lymphokine receptors on T cells. It also enhances lymphocyte responses by activating T4 helper cells. Furthermore, this product may affect the chemotaxis of NK precursor cells, making them more cytotoxic after exposure to interferon. Furthermore, this product can enhance the body's resistance to radiation. Therefore, this product has the effect of regulating and enhancing the body's cellular immune function.
