Product Overview
[Drug name]
Generic name: Shuangzuotai vaginal effervescent tablets
Trade name: Dongyao Shuangzuotai vaginal effervescent tablets 7 tablets
Pinyin full code: DongYao ShuangZuoTaiYinDaoPaoTengPian
[Main ingredients]
This product is a compound preparation, each tablet contains 0.2g of metronidazole, 0.16g of clotrimazole, and 0.008g of chlorhexidine acetate. Excipients are: tartaric acid, microcrystalline cellulose, sodium bicarbonate, hydroxypropyl cellulose, lactose, sodium carboxymethyl starch, polysorbate 80, silicon dioxide, talc.
[Properties]
This product is a white or off-white tablet with slight scars on the surface.
[Indications/Main functions]
It is used for bacterial vaginosis, candidal vulvovaginal disease, trichomoniasis vaginitis, and mixed bacterial, fungal, and trichomoniasis vaginitis.
[Specification]
7 tablets (Eastern medicine)
[Usage and Dosage]
Vaginal administration. Place this product in the posterior fornix of the vagina, 1 tablet at a time, once a day. 7 consecutive days of use is a course of treatment, and a course of treatment is repeated after the first menstruation after stopping the drug.
[Adverse Reactions]
Occasionally, rash, vaginal burning sensation, itching or other mucosal irritation symptoms are seen. Because this product can be absorbed from the mucosa, long-term and large-scale use can also produce the same adverse reactions as systemic medication. Such as nausea, lack of appetite, vomiting, diarrhea, abdominal discomfort, taste changes, dry mouth, metallic taste in the mouth, etc. Epileptic seizures and peripheral neuropathy, the latter is mainly manifested as numbness and paresthesia of the extremities. Others include reversible neutropenia. Allergic reactions such as rash, urticaria, itching, etc. Central nervous system symptoms, such as headache, dizziness, syncope, paresthesia, limb numbness, ataxia and mental confusion. Elevated serum aminotransferase, fever, cystitis, dysuria, dark urine, etc. are all reversible and will recover on their own after stopping the medication.
[Contraindications]
1. Patients who are allergic to pyrrole (imidazole) drugs are contraindicated.
2. Patients with active central nervous system diseases and blood diseases are contraindicated.
3. Pregnant women are contraindicated.
[Precautions]
1. This product is only for vaginal administration and should not be taken orally.
2. Avoid menstruation when using this product.
3. Women with no sexual history should use it under the guidance of a physician.
4. Wash your hands or wear cots or gloves when administering the medicine.
5. If there is a burning sensation, redness, swelling, etc. at the medication site, stop taking the medicine and wash the local medicine off. Consult a physician if necessary.
6. Pay attention to personal hygiene during medication, prevent repeated infection, use condoms or avoid sexual intercourse.
7. Lactating women should stop breastfeeding when using this product.
8. Elderly people should use it with caution.
9. If allergic symptoms or adverse reactions of the central nervous system occur during use, the drug should be discontinued immediately.
10. Use with caution in patients with impaired liver and kidney function.
11. When treating vaginal trichomoniasis, the sexual partner must be treated at the same time.
12. Do not drink alcohol or beverages containing alcohol while taking this product.
13. It is forbidden for those who are allergic to this product, and should be used with caution by those with allergic constitution.
14. It is forbidden to use this product when its properties change.
15. Please keep this product out of reach of children.
16. If you are using other drugs, please consult a doctor or pharmacist before using this product.
[Drug Interactions]
1. Chlorhexidine is incompatible with soap, potassium iodide, etc. It is also incompatible with borax, bicarbonate, carbonate, oxide, citrate, phosphate and sulfate. 2. When this product is used in combination with oxytetracycline, the latter may interfere with the effect of metronidazole in removing vaginal trichomoniasis. 3. Long-term and large-scale use, after absorption through the mucosa, may also produce drug interactions similar to systemic medication, such as inhibiting the metabolism of warfarin and other oral anticoagulants, interfering with disulfiram metabolism and serum aminotransferase and lactate dehydrogenase assay results, and combining with liver microsomal enzyme inducers or inhibitors to accelerate or slow down the metabolism of this product in the liver. 4. If used with other drugs at the same time, drug interactions may occur. Please consult a physician or pharmacist for details.
[Pharmacology and Toxicology]
The metronidazole contained in this product is an anti-anaerobic and anti-trichomonal drug; clotrimazole is a broad-spectrum antifungal drug that has antibacterial effects on a variety of superficial and deep fungi. Its mechanism of action is to inhibit the synthesis of fungal cell membranes and affect their metabolic processes; chlorhexidine acetate is a quaternary ammonium salt cationic surfactant that has a bactericidal effect on Gram-positive bacteria. The combination of the three drugs has a synergistic effect, which is not only suitable for simple fungal, bacterial or trichomonal infections, but also for mixed infections.
[Storage]
Light-shielded and sealed, stored in a dry place
[Packaging]
Aluminum-plastic packaging, 7 pieces × 1 plate/box.
[Validity period]
24 months
[Approval number]
National Medicine Standard H20064179
[Manufacturer]
Shandong Fangming Pharmaceutical Group Co., Ltd.
