Product Overview
[Drug Name]
Generic Name: Thymosin Enteric-Coated Tablets
Trade Name: Xiren Thymosin Enteric-Coated Tablets 10mg*20 Tablets
Pinyin Full Code: XiRen XiongXianZuoChangRongPian 10mg*20 Tablets
[Main Ingredients]
The main ingredient of this product is thymosin, a biologically active polypeptide extracted from the thymus of healthy calves.
[Properties]
This product is an enteric-coated tablet that appears off-white or light yellow after removal of the coating.
[Indications/Main Functions]
Indicated for:
① For patients with chronic hepatitis B aged 18 years and above, who experience decreased cellular immunity due to thymus atrophy after age 18;
② For various primary or secondary T-cell deficiency diseases;
③ For certain autoimmune diseases (such as rheumatoid arthritis and systemic lupus erythematosus);
④ For various diseases with decreased cellular immunity; and as an adjunctive treatment for tumors.
[Specifications]
10mg*20 tablets (Xiren)
[Dosage and Administration]
Oral administration: 2-5 tablets three times daily or as directed by a physician.
[Adverse Reactions]
1. Well tolerated. Some may experience adverse reactions such as nausea, fever, dizziness, chest tightness, and weakness. A few patients may experience occasional drowsiness.
2. Patients with chronic hepatitis B may experience a transient increase in ALT levels when using this product. If there are no signs of liver failure, this product can continue to be used.
[Contraindications]
This product is contraindicated in patients with allergic reactions or organ transplant recipients.
[Drug Interactions]
1. This product can be used in combination with many commonly used medications, including interferon, anti-inflammatory drugs, antibiotics, hormones, analgesics, antihypertensive drugs, diuretics, cardiovascular medications, central nervous system medications, and contraceptives, without any interference.
2. This product has a synergistic effect with interferon in improving immune function.
[Precautions]
1. This product exerts its therapeutic effect by enhancing the patient's immune function. Therefore, it should not be used in patients receiving immunosuppressive therapy (e.g., organ transplant recipients) unless the benefits clearly outweigh the risks.
2. Liver function should be monitored regularly during treatment.
3. Use with caution in patients under 18 years of age.
[Overdose]
There have been no reports of human overdose (therapeutic or accidental). Animal toxicity studies have shown no adverse reactions at doses below 10 mg/kg (the highest dose currently used in studies).
[Pharmacology and Toxicology]
This product is an immunomodulatory drug. It regulates and enhances human cellular immune function. It promotes the maturation of T lymphocytes in peripheral blood after mitogen activation, increases the secretion of various lymphokines (such as interferon-α and interferon-γ, interleukin-2, and interleukin-3) by T cells in response to various antigens or mitogens, and increases the levels of lymphokine receptors on T cells. It also enhances lymphocyte responses by activating T4 helper cells. In addition, this product may affect the chemotaxis of NK precursor cells, which become more cytotoxic after exposure to interferon. Therefore, this product has the effect of regulating and enhancing the human cellular immune function.
