Product Overview
[Drug Name]
Generic Name: Bambuterol Hydrochloride Tablets
Trade Name: LiKeFei
English Name: Bambuterol Hydrochloride Tablets
Chinese Pinyin: YanSuanBanButLuoPian (LiKeFei) (HaiXin)
[Ingredients]
The main ingredient of this product is: Bambuterol hydrochloride. Its chemical name is: 1-[Bis-(3,5-N,N-dimethylcarbamoyloxy)phenyl]-2-N-tert-butylaminoethanol hydrochloride.
[Properties]
This tablet is white or off-white.
[Indications]
For bronchial asthma, chronic asthmatic bronchitis, obstructive pulmonary emphysema, and other lung diseases associated with bronchospasm.
[Dosage and Administration]
Take orally once nightly before bed. The initial dose for adults is 10 mg. Depending on clinical response, the dose may be increased to 20 mg after 1-2 weeks of treatment. For patients with renal insufficiency (GFR <50 ml/min), the recommended initial dose is 5.0 mg.
[Adverse Reactions]
Tremors, headaches, myotonic spasms, and palpitations may occur, but these adverse reactions are milder than those of other similar drugs. Their severity is positively correlated with dose, and most side effects resolve spontaneously within the first one to two weeks of treatment. A very small number of patients may experience mild elevations in transaminases, dry mouth, dizziness, and stomach discomfort.
[Contraindications]
This drug should not be used in patients with allergies to terbutaline, terbutaline, or sympathomimetic amines.
[Precautions]
1. Use with caution in patients with hypertension, heart disease, diabetes, or hyperthyroidism. Patients with diabetic asthma should strengthen blood sugar control when using this drug.
2. This drug is not suitable for patients with cirrhosis or certain liver dysfunctions.
3. The initial dose should be reduced for patients with renal insufficiency.
[Use in Special Populations]
Precautions for Children:
The pediatric dosage has not been established; use with caution in infants and young children.
Precautions for Pregnancy and Lactation:
Use with caution.
Precautions for Elderly:
Use with caution; the initial dose should be reduced.
[Drug Interactions]
1. Combination with other sympathomimetic amines may enhance the effect and increase toxicity. 2. Concomitant use with adrenergic receptor blockers (such as propranolol) is not recommended.
[Pharmacological Actions]
This product is converted to terbutaline in the body, an adrenaline-β2 receptor agonist that relaxes bronchial smooth muscle and achieves an antiasthmatic effect.
[Storage]
Store in a sealed container.
[Strength]
10 mg
[Packaging Specifications]
10 mg x 10 tablets/box.
[Expiration Date]
24 months
[Approval Number]
National Medicine Standard H20030683
[Manufacturer]
Company Name: Xi'an Haixin Pharmaceutical Co., Ltd.
