Product Overview
[Drug Name]
Generic Name: Ambroxol Hydrochloride and Clenbuterol Hydrochloride Tablets
Trade Name: Yitanjing
English Name: Ambroxol Hydrochloride and Clenbuterol Hydrochloride Tablets
Chinese Pinyin: Anxiuteluo Pian
[Ingredients]
This product is a combination preparation consisting of ambroxol hydrochloride and clenbuterol hydrochloride.
[Properties]
This product is a yellow, round tablet.
[Indications]
For the treatment of cough, thick sputum, difficulty expectorating, and wheezing caused by acute and chronic respiratory diseases (such as acute and chronic bronchitis, bronchial asthma, and emphysema).
[Dosage and Administration]
Children over 12 years of age and adults: Oral, one tablet twice daily. For patients with severe respiratory distress, take one tablet three times daily for the first two to three days.
[Adverse Reactions]
This product is well tolerated, with occasional mild gastrointestinal reactions and rashes. Some patients may experience mild dry mouth, hand tremors, dizziness, and palpitations, which resolve upon discontinuation of the drug. 1) Neuropsychiatric: Occasionally, headache, hand tremors, drowsiness, restlessness, dizziness, insomnia, excitement, and numbness of the limbs may occur. 2) Circulatory: Occasionally, palpitations, tachycardia, elevated blood pressure, and irregular heartbeat may occur. 3) Hypersensitivity: Occasionally, allergic rashes may occur, and in some patients with specific constitutions, systemic hypersensitivity reactions may occur, manifesting as itching, bronchospasm, hypotension, and collapse. In these cases, the drug should be discontinued. 4) Other: Occasionally, elevated ALT and AST levels, fatigue, and gastrointestinal discomfort may occur.
[Contraindications]
1. Contraindicated in patients with hypertrophic cardiomyopathy.
2. Contraindicated in patients with allergic reactions to this product.
[Precautions]
1. Use with caution in athletes.
2. Use with caution in patients with hyperthyroidism, hypertension, heart disease (such as heart failure and arrhythmia), diabetes, and severe renal insufficiency.
3. There have been reports of beta-2 agonists causing a decrease in serum potassium levels. Xanthines, steroids, and diuretics may exacerbate the serum potassium-lowering effect of beta-2 agonists, so special caution should be exercised when used together. Hypoxemia, in particular, can significantly affect heart rhythm, so serum potassium should be monitored.
[Use in Special Populations]
Precautions for Children: This product is not designed for use in children under 12 years of age.
Precautions for Pregnancy and Lactation: In animal studies (rat studies), use of this product in late pregnancy has been reported to inhibit uterine smooth muscle contractions, leading to delayed delivery and placental pain. The safety of this product for the fetus is unknown. Therefore, it should be used with caution in pregnant women, especially those within the first three months of pregnancy. This product is excreted in breast milk, so it should be used with caution in lactating women.
Precautions for the Elderly: Due to decreased physiological function in the elderly, a reduced dosage should be used.
[Drug Interactions]
1. Studies have shown that ambroxol can increase the concentration of antibiotics in the respiratory tract.
2. Concomitant use with catecholamines such as epinephrine and isoproterenol can cause arrhythmias and should not be used together.
3. Patients currently taking MAO inhibitors or tricyclic antidepressants should exercise caution when taking this product, as this may enhance its effects on the vascular system.
4. Concomitant use with non-selective beta-blockers such as propranolol is contraindicated.
5. Patients currently taking large amounts of other sympathetic stimulants should exercise caution when taking this product.
[Pharmacological Actions]
Ambroxol hydrochloride is a combination preparation consisting of ambroxol hydrochloride and clenbuterol hydrochloride. Ambroxol hydrochloride is a mucolytic agent that increases secretion of serous glands in the respiratory mucosa, decreases mucous gland secretion, reduces sputum viscosity, promotes the secretion of pulmonary surfactant, and increases bronchial ciliary motility, making sputum easier to expectorate. Clenbuterol hydrochloride is a selective beta-receptor agonist that relaxes bronchial smooth muscle, enhances ciliary motility, dissolves mucus, and promotes sputum discharge.
[Storage]
Store in a dark, sealed container.
[Specifications]
10 tablets
[Packaging]
Box
[Expiration Date]
36 months
[Approval Number]
National Medicine Standard H20080487
[Manufacturer]
Beijing Hanmi Pharmaceutical Co., Ltd.
