Product Overview
[Drug Name]
Generic Name: Valsartan and Amlodipine Tablets (I)
Trade Name: Jinbaoping Valsartan and Amlodipine Tablets (I) 14 Tablets
Pinyin Full Code: JinBaoPing ZuoShaTanAnLvDiPingPian (I) 14 Tablets
[Main Ingredients]
This product is a compound preparation, containing 80mg of valsartan and 5mg of amlodipine per tablet.
[Properties]
This product is a film-coated tablet that appears white or off-white after removal of the coating.
[Indications/Main Functions]
Treatment of essential hypertension. This product is used for patients whose blood pressure cannot be adequately controlled with monotherapy.
[Specifications]
14 tablets
[Dosage and Administration]
Amlodipine 2.5mg to 10mg once daily is effective for the treatment of hypertension, while the effective dose of valsartan is 80mg to 320mg. In clinical trials of once-daily valsartan-amlodipine tablets, using 5mg-10mg of amlodipine and 80mg-320mg of valsartan, the antihypertensive effect increased with increasing dose. Adverse reactions of valsartan are generally dose-independent; adverse reactions of amlodipine are both dose-dependent (primarily peripheral edema) and dose-independent, with the former being more common than the latter. This product can be used as an alternative for patients whose blood pressure is not adequately controlled with monotherapy. Add-on therapy: Patients whose blood pressure is not adequately controlled with amlodipine or valsartan monotherapy can be treated with this product in combination therapy. Patients who experience dose-limiting adverse reactions with amlodipine or valsartan monotherapy can be treated with this product, combining a lower dose of the single component with the other component to achieve blood pressure control. The majority of the therapeutic effect is generally achieved within two weeks of initiation or dose change. Alternative therapy: For ease of administration, patients receiving amlodipine and valsartan combination therapy can be treated with this product at the same dose. Amlodipine and valsartan can be taken with or without food. It is recommended that this product be taken with water. No dosage adjustment is required for patients with mild or moderate renal impairment. Use with caution in patients with severe renal impairment (see [Contraindications]). This product should also be used with caution in patients with hepatic impairment or biliary obstructive disease (see [Precautions]).
[Adverse Reactions]
See the package insert for details.
