Product Overview
[Drug name]
Generic name: Children's paracetamol and amantadine granules
Trade name: Jintong Children's paracetamol and amantadine granules 6g*9 bags
Pinyin full code: JinTong XiaoErAnFenWanAnKeLi 6g*9Dai
[Main ingredients]
This product is a compound preparation, each package contains 0.1g of acetaminophen, 0.04g of amantadine hydrochloride, 4mg of artificial bezoar, 6mg of caffeine, and 0.8mg of chlorpheniramine maleate. Excipients: appropriate amount of powdered sugar and appropriate amount of tartrazine.
[Properties]
This product is a slightly yellow granule.
[Indications/Main functions]
It is suitable for relieving symptoms such as fever, headache, sore limbs, sneezing, runny nose, nasal congestion, and sore throat caused by common colds and influenza in children. It can also be used for the prevention and treatment of influenza in children.
[Specification]
6g*9 bags
[Usage and Dosage]
Oral administration for children aged 1-2 years: half a bag at a time or reduce as appropriate; 2-5 years old: 1 bag each time; 5-12 years old: 1-2 bags each time. Twice a day or as directed by a doctor. Take with warm water.
[Adverse Reactions]
Sometimes there is mild dizziness, fatigue, nausea, upper abdominal discomfort, dry mouth, lack of appetite and rash, etc., which can recover on their own.
[Contraindications]
1. It is contraindicated for patients with severe liver and kidney dysfunction.
2. Due to the lack of safety and efficacy data for newborns and infants under 1 year old, this product is contraindicated for newborns and infants under 1 year old.
[Precautions]
1. If the symptoms are not relieved after 3-7 days of medication, please consult a doctor or pharmacist.
2. Children under 1 year old should use it under the guidance of a doctor.
3. Do not drink alcohol or alcoholic beverages while taking this product.
4. Do not take other anti-cold medicines with similar ingredients to this product at the same time.
5. Use with caution in patients with impaired liver function, renal function, history of mental illness or epilepsy.
6. If overdose or serious adverse reactions occur, seek medical attention immediately.
7. It is forbidden to use in those who are allergic to this product, and it should be used with caution in those with allergic constitution.
8. It is forbidden to use this product when its properties change.
9. Please keep this product out of reach of children.
10. Children must use it under adult supervision.
11. If you are using other drugs, please consult a doctor or pharmacist before using this product.
[Drug Interactions]
1. Use with other antipyretics and analgesics may increase the risk of nephrotoxicity. 2. This product should not be used with chloramphenicol, barbiturates (such as phenobarbital), etc. 3. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.
[Drugs for Children]
Children under 1 year old should use it under the guidance of a doctor.
[Drugs for Elderly Patients]
Due to decreased liver and kidney function, it should be used with caution.
[Pregnant and lactating women]
Amantadine, acetaminophen, and artificial bezoar in this product can all pass through the placenta, which may have adverse effects on the fetus, are toxic to the embryo, and can cause teratogenesis; except for artificial bezoar, which is unknown, all can be secreted through breast milk, so pregnant and lactating women are prohibited from using it.
[Overdose]
Overdose should be closely observed for side effects and poisoning, and blood pressure, pulse, respiration, and body temperature should be monitored. If more than 8 tablets are taken, nausea, vomiting, stomach pain or stomach cramps, diarrhea, anorexia, and hyperhidrosis may occur quickly, and may last for 24 hours. Liver damage occurs within 2 to 4 days, manifested as pain in the liver area, hepatomegaly, and jaundice. In case of overdose, gastric lavage, vomiting, large amount of fluid supplementation and diuresis, acidification of urine to increase drug excretion should be performed immediately, and acetylcysteine, an antagonist of acetaminophen, should be given. Activated carbon should not be given because it may affect the absorption of antidotes; acetylcysteine is first taken orally at 140 mg/kg, and then 70 mg/kg is taken once every 4 hours, for a total of 17 times; intravenous administration can be used in severe cases, and antagonists should be used early. The effect is satisfactory within 12 hours, and the effect is poor after more than 24 hours. At the same time, other symptomatic and supportive therapies should be given. Observe for excessive movements, convulsions, arrhythmias, and hypotension, and give sedatives, anticonvulsants, and antiarrhythmic drugs as needed. To control the symptoms of central nervous system poisoning, physostigmine can be slowly injected intravenously.
[Pharmacology and Toxicology】
Acetaminophen can inhibit the synthesis of prostaglandins and has antipyretic and analgesic effects; amantadine can resist "sub-type A" influenza virus and inhibit virus reproduction; caffeine is a central nervous system stimulant, which can enhance the antipyretic and analgesic effects of acetaminophen, and can reduce the central nervous system inhibitory effects such as drowsiness and dizziness caused by other drugs; chlorpheniramine maleate is an antiallergic drug that can relieve symptoms such as runny nose, nasal congestion, and sneezing; artificial bezoar has antipyretic and tranquilizing effects. The above-mentioned drugs are combined to make a compound, which can enhance the antipyretic and analgesic effects and relieve or improve various symptoms caused by colds.
[Pharmacokinetics]
It is not clear yet.
[Storage】
Sealed, stored in a cool and dry place
[Packaging]
Aluminum-plastic film bag packaging, 9 bags/box
[Validity period]
24 months
[Approval number]
National Medicine Approval No. H21022722
[Manufacturer]
Shenyang Jinchang Pharmaceutical Co., Ltd.
