Product Overview
[Drug Name]
Generic Name: Compound Kendir Leaves Tablets I
Trade Name: Compound Kendir Leaves Tablets I (Juwang)
English Name: Compound Kendir Leaves Tablets I
Chinese Pinyin: Fufang Luobuma Pian
[Ingredients]
This product is a compound preparation. Each 1000 tablets contains: 218.5g of Apocynum venetum leaves, 171.0g of Chrysanthemum indicum, 184.2g of Stephania tetrandra, 15.0g of magnesium trisilicate, 1.6g of hydralazine sulfate, 1.6g of hydrochlorothiazide, 1.05g of promethazine hydrochloride, 0.5g of vitamin B1, 0.5g of vitamin B6, and 0.25g of calcium pantothenate.
[Properties]
This product is a sugar-coated tablet. After removing the sugar coating, it is gray-brown in color, has a slight aroma, and a bitter, astringent taste.
[Indications]
For antihypertensive use.
[Dosage and Administration]
Oral administration. Take 2 tablets at a time, 3 times daily. Maintenance dose: 2 tablets per day.
[Adverse Reactions]
No adverse reactions have been reported.
[Contraindications]
This product is contraindicated in patients with allergies to this product.
[Precautions]
1. Use with caution in patients with hypertension associated with diabetes or gout. 2. High doses of this product can cause central nervous system sedation; use with caution when operating a vehicle or working at heights. 3. Do not use if the drug's properties change.
[Use in Special Populations]
Precautions for Children: Reduce the dose or follow a doctor's advice.
Precautions for Pregnancy and Lactation: This product is not the first choice for pregnant or lactating women with hypertension.
Precautions for the Elderly: Not known.
[Drug Interactions]
Not known.
[Pharmacological Actions]
Administered orally at a dose of 0.2g/kg to dogs with experimental renal hypertension, this product significantly lowered blood pressure from 190/142 mmHg to 153/98 mmHg two hours after oral administration. Oral administration of 0.2g/kg and 0.4g/kg of this drug to dogs and cats slowed the heart rate 20 minutes later, lasting for 5 hours. Oral administration of 0.3g/kg and 0.6g/kg of this drug to rats significantly antagonized arrhythmias induced by aconitine, calcium chloride, and coronary artery ligation. Its antiarrhythmic mechanism may be related to its effect on calcium influx. Oral administration of 0.6g/kg and 1.2g/kg of this drug to mice reduced spontaneous activity and exhibited a synergistic effect with sodium pentobarbital, increasing the loss of righting reflex.
[Storage] Store in a dark, airtight container.
[Specification] 100 tablets
[Packaging] Bottle
[Expiration Period] 24 months
[Approval Number] National Medicine Standard H36021902
[Manufacturer] Company Name: Jiangxi Juwang Pharmaceutical Co., Ltd.
