Product Overview
[Drug name]
Generic name: Compound Medroxyprogesterone Acetate Capsules
Trade name: Fu Fu Chun
English name: Compound Medroxyprogesterone Acetate Capsules
Chinese Pinyin: Cusuan Jiaqiangyuntong Fuhe Jiaonang
[Ingredients]
This product is a compound preparation, and its components are 0.25mg of medroxyprogesterone acetate, 0.625g of ethinyl estradiol, calcium gluconate and vitamins E, A, D, etc. per capsule.
[Properties]
This product is a capsule, and the content is light yellow powder.
[Indications]
It is used for women over 40 years old with menopausal syndrome to relieve and improve symptoms caused by lack of estrogen, progesterone, calcium and vitamins: 1. Hot flashes, sweating, irritability and insomnia, osteoporosis, muscle and joint pain. 2. Dry skin, itching, wrinkles, pigmentation, age spots, dry eyes. 3. Palpitations, chest tightness and shortness of breath, hyperlipidemia, menopausal coronary heart disease, menopausal blood pressure fluctuations; 4. Menstrual disorders, vulvar itching, vaginitis, sexual intercourse pain, sexual organ decline, etc. 5. It can also be used for non-malignant tumors, hysterectomy, oophorectomy and other reasons caused by decreased estrogen levels.
[Usage and Dosage]
Oral.
1. For women who have menopausal syndrome symptoms, the treatment dose is once a day, 2 capsules at a time, 3 months as a course of treatment, and after two courses of treatment, it can be changed to a maintenance dose, once a day, 1 capsule at a time.
2. For women who have menopausal syndrome symptoms, they should insist on taking it every day; for women who have not yet menopausal syndrome symptoms, they should stop taking it after 20 days of menstruation every month, and continue taking it on the 5th day of menstruation next month.
3. Before the age of 45, if there are only symptoms of menstrual disorders, shortened or prolonged cycles, reduced menstrual blood volume, etc., you can take it every other day or once a day, 1 pill at a time, for a total of 20 days and stop for 10 days. If you have menstruation within 10 days, you can repeat it on the 5th day of menstruation for 3 consecutive months; if you do not have menstruation within 10 days, repeat it from the 11th day and take it for 3 to 6 months.
4. For women who have been menopausal for 10 years or are over 60 years old and have symptoms of menopausal syndrome, the first month is the appropriate dose, once a day, 1 pill at a time. If the effect is obvious, you can continue to take it; if the effect is not obvious, change it to once a day, 2 pills at a time in the second month. 3 months is a course of treatment. After the symptoms disappear, consolidate for 3 months and change to the maintenance dose, once a day, 1 pill at a time.
5. Patients with severe menopausal syndrome can increase the dose appropriately under the guidance of a doctor.
6. Patients who have used estrogen alone and still have a uterus can switch to medroxyprogesterone acetate compound capsules. There are two situations: for those who have not reached menopause, they can take 2 capsules once a day during menstruation; for women who have reached menopause, they should first do B-ultrasound to measure the thickness of the endometrium. If it exceeds 0.5cm, they should take medroxyprogesterone acetate (6-10mg for 10 days) under the guidance of a doctor after withdrawal bleeding, and then take this medicine; if the hyperplasia is severe (more than 0.9cm), they should take this medicine after curettage and pathological examination to exclude endometrial cancer.
7. The time of taking medicine should be fixed. Take the medicine before 8 am every day; patients with insomnia can take the medicine half an hour after dinner.
[Adverse reactions]
1% of women who have reached menopause within 5 years will have 1-3 small amounts of bleeding similar to menstruation after taking the medicine. Stop the medicine when bleeding, and take it again after the blood is clean. If the amount of blood is large, go to the gynecology department for treatment. Breast swelling, if it is painful, the dosage should be appropriately reduced.
[Contraindications]
1. Patients with breast, uterine, and ovarian malignant tumors are prohibited. 2. Patients with endometriosis who have not yet reached menopause are prohibited. 3. Patients with acute thrombotic diseases are prohibited. 4. Patients with unexplained vaginal bleeding are prohibited. 5. Patients with uterine fibroids who have not yet reached menopause are prohibited. 6. Pregnant and lactating women are prohibited.
[Precautions] 1. Pregnant or lactating women are prohibited. 2. For high-risk groups, such as those with coronary heart disease, family history of breast, uterine, and ovarian malignant tumors, it should be used with caution. 3. Patients who take it for a long time should undergo regular gynecological examinations. 4. Patients with severe liver and kidney dysfunction should not use it. 5. It is prohibited to use when the properties of the drug change.
[Medication for special populations]
Precautions for children: not yet clear.
Precautions for pregnancy and lactation: Precautions for pregnant and lactating women.
Precautions for the elderly: not yet clear.
[Drug interactions]
Not yet clear. 【Pharmacological Action】
The ethinyl estradiol in this product is a derivative synthesized from the human estrogen estradiol. Estrogen promotes the development, maturation and maintenance of female organs and secondary sexual characteristics by specifically binding to estrogen receptors in target tissue cells, and also has effects on the body's metabolism, cardiovascular, and bones. Medroxyprogesterone acetate is a progestin that inhibits endometrial cell mitosis, reduces the level of endometrial cell estradiol receptors, and increases the activity of estradiol dehydrogenase and isocitrate dehydrogenase, thereby reducing the occurrence of endometrial cancer. When estrogen is used alone, it can cause hyperplasia of the endometrium and breast ducts, and medroxyprogesterone acetate can inhibit this. The incidence of endometrial cancer in menopausal women using estrogen-progesterone combination preparations is significantly lower than that of non-users.
[Storage]Store in a sealed, cool, dry place (not exceeding 20°C).
[Packing Specifications]10 capsules/box.
[Expiration Date]36 months.
[Approval number] National Medicine Standard H20003844
[Manufacturer] Company name: Beijing Kangbid Pharmaceutical Co., Ltd.
