Product Overview
[Drug name]
Generic name: Shuangzuotai vaginal effervescent tablets
Trade name: Qinzhilan Shuangzuotai vaginal effervescent tablets 7 tablets
Pinyin full code: BiZhiLan ShuangZuoTaiYinDaoPaoTengPian 7Pian
[Main ingredients]
This product is a compound preparation, each tablet contains the main ingredients of metronidazole 0.2g, clotrimazole 0.16g, chlorhexidine acetate 0.008g.
[Properties]
This product is a white or off-white tablet with slight hidden spots on the surface.
[Indications/Main functions]
For bacterial vaginitis, candidal vulvovaginal and trichomonal vaginitis, as well as mixed bacterial, fungal, and trichomonal infection vaginitis.
[Specifications]
7 tablets
[Usage and dosage]
Vaginal administration. Place this product in the posterior fornix of the vagina, 1 tablet at a time, once a day. Continuous use for 7 days is a course of treatment, and a course of treatment is repeated after the first menstruation after discontinuation of the drug.
[Adverse Reactions]
Occasionally, rash, vaginal burning sensation, itching or other mucosal irritation symptoms may occur. Because this product can be absorbed from the mucosa, long-term and large-scale use may also produce the same adverse reactions as systemic medication, such as nausea, lack of appetite, vomiting, diarrhea, abdominal discomfort, taste changes, dry mouth, metallic taste in the mouth, etc. Epileptic seizures and peripheral neuropathy, the latter mainly manifested as numbness and paresthesia of the extremities. Others include reversible neutropenia. Allergic reactions such as rash, urticaria, itching, etc. Central nervous system symptoms such as headache, dizziness, syncope, paresthesia, limb numbness, ataxia and mental confusion. Elevated serum aminotransferase, fever, cystitis, dysuria, dark urine, etc. are all reversible and recover on their own after discontinuation of the drug.
[Contraindications]
1. Patients who are allergic to pyrrole (imidazole) drugs are contraindicated. 2. Patients with active central nervous system diseases and blood diseases are prohibited from using this product. 3. Pregnant women are prohibited from using this product.
[Precautions]
1. This product is for vaginal administration only, and should not be taken orally. 2. Avoid using this product during menstruation. 3. Women with no sexual history should use this product under the guidance of a physician. 4. Wash your hands or wear cots or gloves when administering this product. 5. If there is a burning sensation, redness, swelling, etc. at the medication site, stop taking the drug, wash the local drug, and consult a physician if necessary. 6. Pay attention to personal hygiene during medication, prevent repeated infection, use condoms or avoid sexual intercourse. 7. Lactating women should stop breastfeeding when using this product. 8. Elderly people should use this product with caution. 9. If allergic symptoms or adverse reactions to the central nervous system occur during use, stop taking the drug immediately. 10. Use this product with caution in patients with liver or kidney dysfunction. 11. When treating vaginal trichomoniasis, it is necessary to treat their sexual partners at the same time. 12. Do not drink alcohol or beverages containing alcohol while taking this product.
Please read the instructions carefully and use it as directed by your doctor.
[Drug Interactions]
1. Chlorhexidine is incompatible with soap, potassium iodide, etc. It is also incompatible with borax, bicarbonate, carbonate, oxide, citrate, phosphate and sulfate. 2. When this product is used in combination with oxytetracycline, the latter may interfere with the effect of metronidazole in clearing vaginal Trichomonas. 3. Long-term and large-scale use after mucosal absorption may also produce drug interactions similar to systemic medications, such as inhibiting the metabolism of warfarin and other oral anticoagulants, interfering with disulfiram metabolism and serum aminotransferase and lactate dehydrogenase assay results, and combining with liver microsomal enzyme inducers or inhibitors to accelerate or slow down the metabolism of this product in the liver. 4. If used with other drugs at the same time, drug interactions may occur. Please consult a physician or pharmacist for details.
[Drugs for children]
It is not clear yet.
[Drugs for elderly patients]
It is not clear yet.
[Drugs for pregnant and lactating women]
Pregnant women are prohibited.
[Drug overdose]
Long-term and large-scale use, after absorption through the mucosa, can also produce drug interactions similar to systemic medication, such as inhibiting the metabolism of warfarin and other oral anticoagulants, interfering with disulfiram metabolism and serum aminotransferase and lactate dehydrogenase assay results, and combining with liver microsomal enzyme inducers or inhibitors to accelerate or slow down the metabolism of this product in the liver.
[Pharmacology and toxicology]
The metronidazole contained in this product is an anti-anaerobic and anti-trichomonal drug; clotrimazole is a broad-spectrum antifungal drug that has antibacterial effects on a variety of superficial and deep fungi, and its mechanism of action is to inhibit the synthesis of fungal cell membranes and affect their metabolic processes; chlorhexidine acetate is a quaternary ammonium salt cationic surfactant that has a bactericidal effect on Gram-positive bacteria. The combination of the three drugs has a synergistic effect, which is not only suitable for simple fungal, bacterial or trichomonal infections, but also for mixed infections.
[Pharmacokinetics]
It is not yet clear.
[Storage】
Room temperature.
[Validity period]
24 months
[Approval number]
National Medicine Standard H20063174
[Manufacturer]
Hainan Linheng Pharmaceutical Co., Ltd.
