Product Overview
[Drug Name]
Generic Name: Bismuth Potassium Citrate Granules
Trade Name: Lizhu Dele Bismuth Potassium Citrate Granules (1g: 110mg) *28 bags
Pinyin Full Code: LiZhuDeLe ZuoZuoSuanZuoJiaKeLi (1g: 110mg) *28Dai
[Main Ingredients]
Each bag contains 0.3g of bismuth potassium citrate (equivalent to 0.11g of bismuth). Excipients: Mannitol, sodium carboxymethylcellulose.
[Properties]
White to pale yellow granules; slightly sweet.
[Indications/Main Functions]
For chronic gastritis and relief of stomach pain, heartburn, and acid reflux caused by excessive gastric acid.
[Specifications]
(1g: 110mg) *28 bags (Lizhu Dele)
[Dosage and Administration]
Oral administration with 30-50ml of warm water. Adults: Take one packet four times daily, with the first three doses half an hour before meals and the fourth dose two hours after dinner. Alternatively, take two packets twice daily, morning and evening.
[Adverse Reactions]
During treatment, an ammonia odor may develop in the mouth, which may cause the tongue coating and stool to turn grayish-black. This will resolve spontaneously upon discontinuation of the medication. Nausea and constipation may occur occasionally.
[Contraindications]
This product is contraindicated in patients with severe kidney disease and pregnant women.
[Precautions]
1. Do not use this product continuously for more than seven days. If symptoms persist, consult a physician or pharmacist.
2. Consult a physician or pharmacist regarding dosage for children.
3. Do not take other bismuth preparations while taking this product, and high doses should not be taken for long periods of time.
4. In case of overdose or serious adverse reactions, seek medical attention immediately.
5. Do not use if you are allergic to this product. Use with caution if you have allergies.
6. Do not use if the product's properties change.
7. Keep out of reach of children. 8. Children must be supervised by an adult before use.
9. If you are taking other medications, consult a physician or pharmacist before using this product.
[Drug Interactions]
1. Milk and antacids may interfere with the effects of this product and should not be taken concurrently.
2. Taking this product concurrently with tetracycline may affect its absorption.
3. Concomitant use with other medications may result in drug interactions; consult a physician or pharmacist for details.
[Pediatric Use]
Unknown.
[Elderly Use]
Unknown.
[Pregnant and Breastfeeding Use]
Contraindicated in pregnant and breastfeeding women.
[Overdose]
Unknown.
[Pharmacology and Toxicology]
The main ingredient of this product is bismuth tripotassium dicitrate. In the acidic environment of the stomach, it forms a diffuse protective layer covering the ulcer surface, preventing the invasion of gastric acid, enzymes, and food. This product also reduces pepsin activity, increases mucin secretion, and promotes the release of prostaglandins from the mucosa, thereby protecting the gastric mucosa. In addition, this product has a killing effect on Helicobacter pylori (HP), thus promoting the healing of gastritis.
[Pharmacokinetics]
It forms an insoluble precipitate in the stomach, with only a small amount of bismuth being absorbed. It is then transported by binding to proteins with a molecular weight of 50,000 or more. Bismuth is primarily distributed in the liver and kidneys and excreted in the urine through the kidneys.
[Storage]
Store in a dry, airtight container protected from light.
[Packaging]
28 bags per box. Packaging material: Composite aluminum film.
[Expiry Period]
36 months
[Approval Number]
National Medicine Standard H10900086
[Manufacturer]
Livzon Pharmaceutical Factory, Livzon Group
