Product Overview
[Drug Name]
Generic Name: Itopride Hydrochloride Tablets
Trade Name: Ruifulin
English Name: Itopride Hydrochloride Tablets
Chinese Pinyin: Yansuan Yituobili Pian
[Ingredients]
The main ingredient of this product is itopride hydrochloride. Chemical Name: N-[4-[2-(dimethylamino)ethoxy]benzyl]-3,4-dimethoxybenzamide hydrochloride
[Appearance]
White tablets.
[Indications]
Gastrointestinal prokinetic drug, indicated for various symptoms associated with functional dyspepsia, such as upper abdominal discomfort, postprandial fullness, loss of appetite, nausea, and vomiting.
[Dosage and Administration]
Adults: 1 tablet three times daily before meals. The dosage may be reduced based on age and symptoms.
[Adverse Reactions]
Digestive System: Occasionally, diarrhea, abdominal pain, constipation, and increased salivation may occur. Neuropsychiatric System: Occasionally, headache and sleep disturbances may occur. Hematological System: Occasionally, leukopenia may occur (if confirmed, discontinue the drug). Allergic symptoms: rash, fever, itching, etc. Occasionally, elevated DUN and creatinine levels may occur. Back pain, fatigue, numbness in the fingers, and hand tremors may also be seen.
[Contraindications]
1. Contraindicated in patients with allergies to this product's ingredients.
2. Contraindicated in patients with gastrointestinal bleeding, mechanical obstruction, or perforation.
[Precautions]
This product may enhance the effects of acetylcholine; caution is advised when using this product in elderly patients, who are particularly susceptible to side effects.
[Use in Special Populations]
Precautions for Children:
Safety data for this product in children have not been established; its use should be avoided.
Precautions for Pregnancy and Lactation:
1. Because its safety in pregnant women has not been confirmed, it should only be used in pregnant women or women of childbearing potential when the therapeutic benefits outweigh the risks.
2. Because it has been reported in animal studies (rat studies) that this product can be transferred into breast milk, breastfeeding should be avoided while taking this product.
Precautions for Elderly Patients:
Due to decreased physiological function in the elderly, adverse reactions are more common. Therefore, elderly patients should be carefully observed after taking this product. If any adverse reactions occur, measures such as dosage reduction or discontinuation should be taken.
[Drug Interactions]
Combined use with anticholinergics and muscle relaxants (such as diazepam and chlorzoxazone) may counteract each other's effects.
[Pharmacological Actions]
It has dual effects of domamine D2 receptor blocking and acetylcholinesterase inhibition. By stimulating the release of endogenous acetylcholine and inhibiting its hydrolysis, it enhances gastric and duodenal motility, promotes gastric evacuation, and has a moderate emetic effect.
[Storage]
Store tightly closed in a cool, dark place.
[Strength]
50mg
[Packaging]
10 tablets per box.
[Expiration Period]
Tentatively 24 months
[Approval Number]
National Medicine Standard H20010186
[Manufacturer]
Company Name: Livzon Pharmaceutical Factory, Livzon Group
