Product Overview
[Drug Name]
Generic Name: Inositol Nicotinate Tablets
Trade Name: Xianweng Inositol Nicotinate Tablets (0.2g x 100 tablets)
[Main Ingredients]
The main ingredient of this product is inositol nicotinate.
[Properties]
This product is white or off-white tablets.
[Indications/Main Functions]
This product is used as an adjunctive treatment for hyperlipidemia, atherosclerosis, and various peripheral vascular disorders (such as arteriosclerosis obliterans, acrovascular spasm, frostbite, and vascular migraine).
[Specifications]
0.2g x 100 tablets
[Dosage and Administration]
Oral, 3 times daily, 0.2-0.6g (1-3 tablets) per dose, for 1-3 months.
[Adverse Reactions]
Mild nausea, sweating, and itching may occur after taking this product.
[Contraindications]
1. This product is contraindicated in patients with allergies to this product or other niacin-based medications. 2. This product is contraindicated in patients with active liver disease, unexplained elevated aminotransferase levels, or other liver dysfunction. It is contraindicated in patients with active ulcer disease or a tendency to bleed.
[Drug Interactions]
Drug interactions may occur if used concurrently with other medications. Please consult your physician or pharmacist for details.
[Precautions]
Patients with achlorhydria should concurrently administer dilute hydrochloric acid or lemon juice to minimize adverse reactions.
[Pediatric Use]
This study has not been conducted and no reliable references are available.
[Elderly Use]
This study has not been conducted and no reliable references are available.
[Overdose]
In the event of an overdose, appropriate supportive care should be implemented for symptoms of toxicity.
[Pharmacology and Toxicology]
This product is a mild peripheral vasodilator that is gradually hydrolyzed in the body to niacin and inositol. It possesses the pharmacological effects of both niacin and inositol, and has lipid-lowering properties. Its vasodilatory effect is milder and more sustained than that of niacin, without the side effects of niacin, such as flushing and stomach discomfort. This product selectively dilates blood vessels in diseased areas and areas sensitive to cold, while having a lesser dilating effect on normal blood vessels. It also has thrombolytic, anticoagulant, anti-fatty liver, and capillary fragility-reducing effects. Toxicology: This product hydrolyzes in the body into niacin and inositol. The LD50 for niacin is 7g/kg (oral) for rats and 5g/kg (subcutaneous) for rats.
