Product Overview
[Drug Name]
Generic Name: Itopride Hydrochloride Capsules
Trade Name: Yitian
English Name: Itopride Hydrochloride Capsules
Chinese Pinyin: Yansuan Yituobili Jiaonang
[Ingredients]
The main ingredient of this product is itopride hydrochloride.
[Properties]
This product is a white powder.
[Indications]
This product is indicated for various symptoms associated with functional dyspepsia, such as upper abdominal discomfort, postprandial fullness, early satiety, loss of appetite, nausea, and vomiting.
[Dosage and Administration]
Adults: 1 capsule (50 mg) three times daily, 20 minutes before meals. Or as directed by a physician.
[Adverse Reactions]
Digestive System: Diarrhea, abdominal pain, constipation, increased salivation. Neuropsychiatric System: Headache, sleep disturbances, dizziness. Hematologic System: Leukopenia (discontinue the drug if confirmed). Allergic Symptoms: Rash, fever, itching, etc. Elevated blood urea nitrogen (BUN) and creatinine levels may occur occasionally. Elevated AST, ALT, and prolactin levels (within the normal range) have been reported. Symptoms such as back pain, fatigue, numbness in the fingers, and hand tremors may also be observed.
[Contraindications]
1. This product is contraindicated in patients with allergies to its ingredients.
2. This product is contraindicated in the presence of gastrointestinal bleeding, mechanical obstruction, or perforation.
[Precautions]
1. This product may enhance the effects of acetylcholine, so caution should be exercised during use.
2. If this product is ineffective, avoid long-term, uncontrolled use.
3. Use with caution in patients with severe hepatic or renal impairment.
4. If a prolonged QTc interval is observed on an electrocardiogram (ECG), discontinue use.
[Use in Special Populations]
Precautions for Children:
Avoid use in children.
Precautions for Pregnancy and Lactation:
Avoid use in pregnant and lactating women.
Precautions for the Elderly:
Since the elderly experience decreased physiological function and are more susceptible to adverse reactions, they should be carefully observed after taking this product. If adverse reactions occur, measures such as reducing the dose or discontinuing the drug should be taken.
[Drug Interactions]
Since anticholinergic drugs such as tiquinolone bromide, scopolamine butylbromide, and thiophenecarb may weaken the gastrointestinal motility-promoting effects of this product, concomitant use with these drugs should be avoided.
[Pharmacological Actions]
Itopride hydrochloride increases acetylcholine release by antagonizing dopamine D2 receptors. It also inhibits the breakdown of released acetylcholine by inhibiting acetylcholinesterase, thereby enhancing gastric and duodenal motility. This product has a positive gastric motility effect, enhancing gastric and duodenal contractility, accelerating gastric emptying, and suppressing vomiting.
[Storage]
Store in a sealed container.
[Strength]
50 mg
[Packaging]
Aluminum-plastic packaging. 10 tablets per plate, per box.
[Expiration Date]
24 months
[Approval Number]
National Medicine Standard H20050721
[Manufacturer]
Company Name: Zhuhai Rundu Pharmaceutical Co., Ltd.
