Product Overview
【Drug name】
Generic name: Children's paracetamol and amantadine granules
Trade name: ShenMiao Children's paracetamol and amantadine granules 12 bags
Pinyin full code: ShenMiao XiaoErAnFenWanAnKeLi 12Dai
【Main ingredients】
This product is a compound preparation, which consists of 0.1g acetaminophen, 0.04g amantadine hydrochloride, 4mg artificial bezoar, 6mg caffeine, and 0.8mg chlorpheniramine maleate. Excipients: sucrose.
【Properties】
This product is a slightly yellow granule.
【Indications/Main functions】
It is used for nasal congestion, runny nose, sneezing, headache, sore throat, fever, etc. caused by colds in children, and can also be used for the prevention and treatment of influenza.
【Specification】
12 bags
【Usage and Dosage】
Oral children aged 1-2 years: half a bag at a time or reduce as appropriate; 2-5 years old: 1 bag each time; 5-12 years old: 1-2 bags each time. Twice a day or as directed by a doctor. Take with warm water.
【Adverse Reactions】
Occasionally, adverse reactions such as granulocytopenia, thrombocytopenia, anorexia, nausea, vomiting, and rash are seen.
【Contraindications】
1. Those who are allergic to any of the ingredients in this product are prohibited.
2. Newborns and children under one year old are prohibited.
3. Patients with active peptic ulcers are prohibited.
【Precautions】
1. If the symptoms are not relieved after 3-7 days of medication, please consult a doctor or pharmacist
2. Do not drink alcohol or alcoholic beverages while taking this product.
3. Do not take other anti-cold drugs with similar ingredients to this product at the same time.
4. Use with caution in patients with liver dysfunction, renal dysfunction, history of mental illness or epilepsy.
5. If you take an overdose or have a serious adverse reaction, you should seek medical attention immediately.
6. It is forbidden to use if you are allergic to this product, and it should be used with caution if you have an allergic constitution.
7. It is forbidden to use this product when its properties change.
8. Please keep this product out of reach of children.
9. Children must use it under adult supervision.
10. If you are using other medicines, please consult a doctor or pharmacist before using this product.
【Drug Interactions】
1. Use with other antipyretics and analgesics may increase the risk of nephrotoxicity. 2. This product should not be used with chloramphenicol, barbiturates (such as phenobarbital), etc. 3. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.
【Drugs for Children】
It is forbidden for children under 1 year old.
【Drugs for Elderly Patients】
It should be used with caution due to decreased liver and kidney function.
【Pregnant and lactating women】
Amantadine, acetaminophen, and artificial bezoar in this product can all pass through the placenta, which may have adverse effects on the fetus, are toxic to the embryo, and can cause teratogenesis; except for artificial bezoar, which is unknown, all can be secreted through breast milk, so pregnant and lactating women are prohibited from using it.
【Overdose】
Overdose should be closely observed for side effects and poisoning, and blood pressure, pulse, respiration, and body temperature should be monitored. If more than 8 tablets are taken, nausea, vomiting, stomach pain or stomach cramps, diarrhea, anorexia, and hyperhidrosis may occur quickly, and may last for 24 hours. Liver damage occurs within 2 to 4 days, manifested as pain in the liver area, hepatomegaly, and jaundice. In case of overdose, gastric lavage, vomiting, large amount of fluid supplementation and diuresis, acidification of urine to increase drug excretion should be performed immediately, and acetylcysteine, an antagonist of acetaminophen, should be given. Activated carbon should not be given because it may affect the absorption of antidotes; acetylcysteine is first taken orally at 140 mg/kg, and then 70 mg/kg is taken once every 4 hours, for a total of 17 times; intravenous administration can be used in severe cases, and antagonists should be used early. The effect is satisfactory within 12 hours, and the effect is poor after more than 24 hours. At the same time, other symptomatic and supportive therapies should be given. Observe for excessive movements, convulsions, arrhythmias, and hypotension, and give sedatives, anticonvulsants, and antiarrhythmic drugs as needed. To control the symptoms of central nervous system poisoning, physostigmine can be slowly injected intravenously.
【Pharmacology and Toxicology】
Acetaminophen can inhibit the synthesis of prostaglandins and has antipyretic and analgesic effects; caffeine is a central nervous system stimulant, which can enhance the antipyretic and analgesic effects of acetaminophen, and can relieve central nervous system inhibition symptoms such as drowsiness and dizziness caused by other drugs; chlorpheniramine maleate is an antihistamine, which can relieve symptoms such as runny nose, nasal congestion, and sneezing; artificial bezoar has antipyretic and sedative effects.
【Pharmacokinetics】
It is not clear yet.
【Storage】
Sealed and stored in a cool place.
【Packaging】
Aluminum film package, 12 bags per box.
【Validity period】
24 months
【Approval number】
National Medicine Standard H13023708
【Manufacturer】
Shenwei Pharmaceutical Group Co., Ltd.
