Product Overview
[Drug Name]
Trade Name: Oliya
English Name: Omeprazole Enteric-coated Capsules
Chinese Pinyin: Omeprazole Enteric-coated Capsules
[Ingredients]
The main ingredient of this product is omeprazole.
[Properties]
This product consists of white or off-white enteric-coated pellets or granules.
[Indications]
Indicated for peptic ulcers (stomach and duodenum), reflux esophagitis, and Zollinger-Ellison syndrome (gastrinoma).
[Dosage and Administration]
Oral administration, do not chew.
1. Peptic ulcer: 20 mg (1 capsule at a time), 1-2 times daily. Swallow once in the morning or once in the morning and evening. The treatment course for gastric ulcers is usually 4-8 weeks, and for duodenal ulcers is usually 2-4 weeks.
2. Reflux esophagitis: 20-60 mg (1-3 capsules at a time), 1-2 times daily. Take once in the morning or once in the morning and evening. The course of treatment is usually 4-8 weeks.
3. Zollinger-Ellison syndrome: Take 60 mg (3 tablets) once daily. The total daily dose can be adjusted to 20-120 mg (1-6 tablets) depending on the condition. If the total daily dose exceeds 80 mg (4 tablets), it should be taken in two divided doses.
[Adverse Reactions]
1. This product is well tolerated. Common adverse reactions include diarrhea, headache, nausea, abdominal pain, gastrointestinal flatulence, and constipation. Occasionally, elevated serum aminotransferases (ALT, AST), rash, dizziness, drowsiness, and insomnia may occur. These adverse reactions are generally mild, resolve spontaneously, and are unrelated to dose.
2. No serious adverse reactions have been observed with long-term treatment, but gastric mucosal cell hyperplasia and atrophic gastritis may occur in some cases.
[Contraindications]
This product is contraindicated in patients with allergies, severe renal insufficiency, and infants and young children.
[Precautions]
1. When treating gastric ulcers, the possibility of ulcer-type gastric cancer should be ruled out first, as this product may alleviate symptoms and thus delay treatment.
2. Use with caution in patients with hepatic and renal insufficiency.
3. This product comes in enteric-coated capsules. Be careful not to chew them when taking to prevent premature release of the drug in the stomach and affecting efficacy.
[Use in Special Populations]
Precautions for Children: There is no experience with this product in children. Infants and young children are contraindicated.
Precautions for Pregnancy and Lactation: Although this product has no teratogenic effects in animal studies, it should generally not be used in pregnant women and should be used with caution in lactating women.
Precautions for the Elderly: Not yet known.
[Drug Interactions]
This product may delay the elimination of drugs metabolized by the liver, such as diazepam, phenytoin, warfarin, and nifedipine. When used with these drugs, the dosage of the latter should be reduced.
[Pharmacological Actions]
1. Proton pump inhibitor. 2. This drug is a fat-soluble, weakly alkaline drug that is easily concentrated in acidic environments. Therefore, after oral administration, it is specifically distributed in the secretory tubules of the gastric parietal cells. In this highly acidic environment, it is converted into its active form, the sulfenamide. This form then irreversibly binds to the sulfhydryl group of the H+, K+-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells via a disulfide bond, forming a sulfenamide-proton pump complex. This inhibits the enzyme's activity and blocks the final step in gastric acid secretion. Therefore, this drug has a strong and long-lasting inhibitory effect on gastric acid secretion caused by various causes.
[Storage]
Store in a dry, airtight container protected from light.
[Strength]
20mg
[Packaging]
20mg x 21 capsules/bottle
[Expiry Date]
24 months.
[Approval Number]
National Medicine Standard H10930087
[Manufacturer]
Company Name: Foshan Shouxin Pharmaceutical Co., Ltd.
