Product Overview
[Drug Name]
Generic Name: Enalapril Maleate Tablets
Trade Name: SHYNDEC
English Name: Enalapril
Chinese Pinyin: Malaisuan yinapuli pian
[Ingredients]
Enalapril Maleate
[Properties]
This product is a white tablet.
[Indications]
For the treatment of essential hypertension.
[Dosage and Administration]
The initial dose is 5-10 mg daily, divided orally in 1-2 doses. For patients with severe renal impairment (creatinine clearance less than 30 ml/min), the daily dose is 2.5 mg. The dose can be gradually increased based on blood pressure levels. The generally effective dose is 10-20 mg daily. The maximum daily dose should generally not exceed 40 mg. It can be used in combination with other antihypertensive drugs, especially diuretics, to significantly enhance the antihypertensive effect. However, it should not be used in combination with potassium-sparing diuretics.
[Adverse Reactions]
May include dizziness, headache, drowsiness, dry mouth, fatigue, upper abdominal discomfort, nausea, chest tightness, cough, rash, flushing, and proteinuria. Reduce the dose if necessary. Discontinue the drug if leukopenia occurs.
[Contraindications]
Contraindicated in patients allergic to this product or with bilateral renal artery stenosis. Use with caution in children, pregnant women, lactating women, and those with severe renal impairment.
[Precautions]
1. In some patients, especially those taking diuretics or experiencing hypovolemia, this may cause an excessive drop in blood pressure. Therefore, the initial dose should be started at 2.5 mg. 2. Regularly monitor white blood cell counts, renal function, and serum potassium.
[Use in Special Populations]
Precautions for Children: Use with caution in children.
Precautions for Pregnancy and Lactation: Use with caution in pregnant and lactating women.
Precautions for Elderly: No studies have been conducted and no reliable references are available.
[Drug Interactions]
Drug interactions may occur if used concurrently with other medications. Consult your physician or pharmacist for details.
[Pharmacological Actions]
Angiotensin-converting enzyme inhibitor. After oral administration, it is hydrolyzed in the body to enalaprilat, which strongly inhibits angiotensin-converting enzyme (ACE), reducing angiotensin II levels, causing systemic vasodilation and lowering blood pressure. It has a significant antihypertensive effect in rat models of dinephrotic hypertension, mononephrotic hypertension, and spontaneous hypertension.
[Storage] Store in a sealed container away from light.
[Strength] 5mg
[Packaging] 5mg x 16s/box
[Expiry Date] 24 months
[Approval Number] National Medicine Standard H31021937
[Manufacturer] Shanghai Modern Pharmaceutical Co., Ltd.
