Product Overview
[Drug Name]
Generic Name: Amlodipine Mesylate Tablets
Trade Name: Xinluoping Amlodipine Mesylate Tablets 5mg x 14 Tablets
[Main Ingredients]
The main ingredient of this product is amlodipine mesylate. Its chemical name is: (±) 2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid, 3-ethyl ester-5-methyl ester methanesulfonate monohydrate. Molecular formula: C₂O₄H₂S₅ClN₂O₅·CH₃SO₃H·H₂O. Molecular weight: 523.00.
[Properties]
This product is white tablets.
[Indications/Main Functions]
Hypertension.
[Specification]
5mg*14 tablets
[Usage and Dosage]
Oral: The initial dose is 5mg (1 tablet) once a day. The dose can be increased according to the patient's clinical response, up to a maximum of 10mg (2 tablets) once a day.
[Adverse Reactions]
This product is well tolerated by patients. A few patients experience mild adverse reactions such as flushing, headache, and edema during medication. A very small number of patients experience mild adverse reactions such as palpitations, fatigue, dizziness, itching, rash, and insomnia. According to literature reports, extremely rare adverse reactions of amlodipine include nausea, abdominal pain, dyspnea, muscle cramps, and indigestion. No abnormal laboratory test parameters related to this product have been found.
[Contraindications]
This product is contraindicated in patients who are allergic to dihydropyridine calcium antagonists.
[Precautions]
(1) The half-life of amlodipine is prolonged when liver function is impaired, but the corresponding recommended dose has not yet been determined. Therefore, patients with impaired liver function should be very cautious when using this product.
(2) Amlodipine is extensively metabolized into inactive metabolites, with only about 5% of the drug excreted unchanged in urine. Changes in its blood concentration are not correlated with the degree of renal impairment. Therefore, patients with renal failure can use a normal dose. This product is not dialyzed.
