Product Overview
[Drug Name]
Generic Name: Domperidone Tablets
Trade Name: Weiliya Domperidone Tablets 10mg x 30 Tablets
Pinyin Full Code: DuoPanLiTongPian
[Main Ingredients]
Each tablet contains 10mg of domperidone. Excipients are: lactose, starch, microcrystalline cellulose, povidone K90, sodium lauryl sulfate, magnesium stearate, and colloidal silicon dioxide.
[Properties]
This product is a white tablet.
[Indications/Main Functions]
Indicated for indigestion, abdominal distension, belching, nausea, vomiting, and abdominal pain.
[Specifications]
10mg x 30 tablets (Weiliya)
[Dosage and Administration]
Oral. Adults: 1 tablet three times daily, 15-30 minutes before meals.
[Adverse Reactions]
1. Mild abdominal cramps, dry mouth, rash, headache, diarrhea, nervousness, fatigue, drowsiness, and dizziness may occasionally occur.
2. Occasionally, elevated serum prolactin levels, galactorrhea, and gynecomastia may occur, but these symptoms return to normal after discontinuation of the drug.
[Contraindications]
This product is contraindicated in patients with pheochromocytoma, breast cancer, mechanical intestinal obstruction, or gastrointestinal bleeding.
[Precautions]
1. Use with caution in pregnant women. Breastfeeding women should discontinue breastfeeding while using this product.
2. Domperidone suspension is recommended for children.
3. Caution is advised in patients with heart disease (arrhythmias) and cancer patients undergoing chemotherapy, as this product may aggravate heart rhythm disorders.
4. In case of overdose or serious adverse reactions, seek medical attention immediately.
5. This product is contraindicated in patients with allergies and should be used with caution in those with allergic constitutions.
6. This product should not be used if its properties change.
7. Keep this product out of reach of children.
8. If you are taking other medications, consult your doctor or pharmacist before using this product.
[Drug Interactions]
1. Do not use with azole antifungals such as ketoconazole and itraconazole, macrolide antibiotics such as erythromycin, HIV protease inhibitors, and nefazodone.
2. Anticholinergic drugs such as tacrolimus, propantheline bromide, anisodamine, and belladonna tablets can weaken the effect of this product and should not be taken with it.
3. Antacids and drugs that inhibit gastric acid secretion can reduce the bioavailability of this product and should not be taken with this product.
4. Concomitant use with other medications may cause drug interactions. Please consult your doctor or pharmacist for details.
[Pediatric Use]
Because the blood-cerebrospinal fluid barrier is not fully developed in children under one year of age, the possibility of central nervous system side effects cannot be ruled out.
[Pregnant and Breastfeeding Use]
Use with caution in pregnant women.
[Pharmacology and Toxicology]
This drug acts directly on the gastrointestinal wall, increasing gastrointestinal motility and tone, promoting gastric emptying, increasing antral and duodenal motility, and coordinating pyloric contractions. It also enhances esophageal motility and lower esophageal sphincter tone, suppressing nausea and vomiting. This drug does not readily cross the blood-brain barrier.
[Pharmacokinetics]
After oral administration, it is rapidly absorbed, reaching peak plasma concentrations within 15-30 minutes. Distribution is highest in the gastrointestinal tract, followed by plasma, with virtually no drug present in the brain. This drug is almost entirely metabolized in the liver, with a half-life (t½) of 7 hours. Urinary excretion accounts for 31.23%, with unchanged drug accounting for 0.4%. Fecal excretion accounts for 65.7%, with unchanged drug accounting for 10%.
[Storage]
Keep out of sight and sealed.
[Expiry Period]
36 months.
[Approval Number]
H20093370
[Manufacturer]
Foshan Shouxin Pharmaceutical Co., Ltd.
