Product Overview
[Drug Name]
Generic Name: Isosorbide Mononitrate Sustained-Release Capsules
Trade Name: Isosorbide
English Name: Isosorbide Mononitrate Sustained-Release Capsules
Chinese Pinyin: ChanXiaoSuanYiShanLiZhiHuanShiJiaoNang
[Ingredients]
Ingredients: The main ingredient of this product is isosorbide mononitrate, chemical name: 1,4:3,6-dianhydro-D-sorbitol-5-nitrate.
[Properties]
This product is a capsule containing a white powder.
[Indications]
Long-term treatment of coronary heart disease; prevention of angina pectoris; treatment of persistent angina pectoris after myocardial infarction; combined with digitalis and/or diuretics for the treatment of chronic congestive heart failure.
[Dosage and Administration]
50 mg sustained-release capsules, taken once daily after breakfast.
[Adverse Reactions]
Nitrates may cause vasodilatory headaches initially, which usually resolve after several days of continuous use. Flushing, dizziness, orthostatic hypotension, and reflex tachycardia may also occur. Rarely, significant hypotension, bradycardia, worsening angina, and syncope may occur.
[Contraindications]
Circulatory failure (shock, circulatory collapse); severe hypotension (systolic blood pressure <90 mmHg); acute myocardial infarction with low filling pressures (unless under continuous hemodynamic monitoring); hypertrophic obstructive cardiomyopathy; constrictive pericarditis or cardiac tamponade; severe anemia; glaucoma; increased intracranial pressure; and hypersensitivity to nitro compounds.
[Precautions]
In patients with acute myocardial infarction and low filling pressures, avoid systolic blood pressures below 90 mmHg. Use with caution in patients with aortic and/or mitral valve stenosis, postural hypotension, and renal insufficiency.
[Use in Special Populations]
Precautions for Children:
Studies for this class of drugs have all been conducted in adults. Comparative data on use in children and adults are unavailable, so use in children is not recommended.
Precautions for Pregnancy and Lactation:
No embryotoxic effects have been observed in animal studies, and it is unknown whether ISMN is excreted in breast milk. However, due to a lack of experience with its use in pregnant and lactating women, caution is advised.
Precautions for Elderly:
Elderly patients may be more sensitive to this class of drugs and may be more susceptible to reactions such as dizziness.
[Drug Interactions]
Combination use with other vasodilators, calcium antagonists, beta-blockers, antihypertensive drugs, tricyclic antidepressants, and alcohol may potentiate the blood pressure-lowering effect of this class of drugs.
[Storage]
Store in a dark, airtight container.
[Specifications]
50mg x 10 tablets
[Approval Number]
National Medical Standard No. H20031224
