Product Overview
Generic Name: Jifazhi Tablets
Trade Name: Huijiaqiang-G
Chinese Pinyin: JiFaZhiPian
Approval Number: H20090150
Manufacturer: Seiko Eiyo Yakuhin Co., Ltd. (Japan)
Related Conditions: Duodenal ulcer, gastric ulcer, gastritis, chronic gastritis, indigestion
Appearance: This product is an orange, round, film-coated tablet.
Main Ingredient: This product's main ingredient is Jifazhi.
Indications: This product is used for gastric and duodenal ulcers, acute and chronic gastritis, hyperacidity, heartburn, abdominal distension, indigestion, jejunal ulcers, and cramps.
Specifications: 50mg x 30 tablets
Adverse Reactions: Occasionally, symptoms such as dry mouth, nausea, palpitations, and constipation may occur. Discontinue use immediately in severe cases.
Dosage and Administration: 1. Adults take two tablets orally three times daily. The typical course of treatment is one month; in severe cases, two to three months is required. 2. Pediatric Use: Take one to two tablets orally three times daily. 3. Maintenance Use: Take one to two tablets orally three times daily. Preventive Use: Take one tablet orally three times daily. 4. Preventive Use: Take one tablet orally three times daily.
Contraindications: None.
Precautions: Use with caution during pregnancy and in patients with contraindications to prostaglandins, such as those with glaucoma.
Use in Pregnant and Breastfeeding Women: Due to the lack of clinical data on this topic, caution is advised for pregnant and breastfeeding women.
Pediatric Use: None. Refer to the Pediatric Dosage and Administration section or take under the guidance of a physician.
Elderly Use: None. Refer to the Adult Dosage section for dosage.
Drug Interactions: None.
Pharmacology and Toxicology: Gefarnate protects the gastric mucosa, promotes ulcer healing, increases gastric mucosal prostaglandins, prevents a decrease in mucosal electrical potential, promotes soluble mucus secretion, increases visible mucus layer thickness, strengthens the gastric mucosal barrier, dilates gastric mucosal microcirculation, and improves blood flow distribution.
Pharmacokinetics: Absorption, Distribution, and Excretion:
A single oral dose of 50 mg/kg of gefarnate showed an absorption rate of 60-70%. Peak blood concentrations reached 6 hours after oral administration. After 24 hours, 12.4% was excreted in urine, 19.5% in expired air, and 30-40% in feces.
Storage: Store in a dry place at room temperature.
Shelf Life: 36 months
