Product Overview
[Drug Name]
Generic Name: Trimebutine Maleate Tablets
Trade Name: ShuangDi Trimebutine Maleate Tablets 0.1g*24 Tablets
Pinyin Code: ShuangDi MaLaiSuanQuMeiBuTingPian 0.1g*24 Tablets
[Main Ingredient]
The main ingredient of this product is trimebutine maleate.
[Properties]
This product is a white film-coated tablet.
[Indications/Main Functions]
Improves symptoms such as loss of appetite, nausea, vomiting, belching, abdominal distension, borborygmi, abdominal pain, diarrhea, and constipation caused by gastrointestinal motility disorders.
[Specifications]
0.1g*24 tablets
[Dosage and Administration]
Adults: Oral: 0.1-0.2g three times daily. The dose may be increased or decreased based on age and symptoms, or as directed by a physician.
[Adverse Reactions]
Occasionally, symptoms include thirst, oral numbness, abdominal borborygmi, constipation, tachycardia, drowsiness, dizziness, headache, rash, and increased GOT and GPT, with an incidence of approximately 0.4%.
[Contraindications]
Contraindicated in patients with hypersensitivity to trimebutine maleate.
[Drug Interactions]
Combined use with proton pump inhibitors accelerates ulcer healing.
[Precautions]
1. Use with caution in pregnant and lactating women and children.
2. Patients who develop a rash should discontinue the drug and observe the patient.
[Pediatric Use]
Use with caution in children.
[Elderly Use]
Elderly patients generally have weaker physiological functions, so a reduced dosage is recommended.
[Overdose]
Unknown.
[Pharmacology and Toxicology]
Direct effects on gastrointestinal smooth muscle. Experiments on isolated guinea pig gastric vestibular circular muscle specimens demonstrated that this drug exhibits direct effects on gastrointestinal smooth muscle even in the presence of atropine, phentolamine, propranolol, and tetrodotoxin. Experiments on isolated guinea pig ileum have shown that this agent can non-competitively inhibit the contraction caused by acetylcholine. Furthermore, it has been found that after the vagus nerve is removed from the chest of anesthetized dogs, it still has a direct effect on digestive tract motility.
