Product Overview
[Drug Name]
Trade Name: Aomeilazuo
English Name: Omeprazole Enteric-coated Tablets
Chinese Pinyin: Aomeilazuo Changrong Pian
[Ingredients]
The main ingredient of this product is omeprazole.
[Properties]
This product is an enteric-coated tablet, which appears white or off-white after removing the coating.
[Indications]
It is suitable for gastric ulcers, duodenal ulcers, stress ulcers, reflux esophagitis, and Zollinger-Ellison syndrome (gastrinoma).
[Dosage and Administration]
Oral administration, do not chew.
1. Peptic ulcer: 20 mg (1 tablet at a time), 1-2 times daily. Swallow once in the morning or once in the morning and evening. The treatment course for gastric ulcers is usually 4-8 weeks, and for duodenal ulcers, it is usually 2-4 weeks.
2. Reflux esophagitis: 20-60 mg (1-3 tablets at a time), 1-2 times daily. Take in the morning or once in the morning and evening. The course of treatment is usually 4 to 8 weeks.
3. Zollinger-Ellison syndrome: Take 60 mg (3 tablets) once daily. The total daily dose can be adjusted to 20 to 120 mg (1 to 6 tablets) depending on the condition. If the total daily dose exceeds 80 mg (4 tablets), it should be taken in two divided doses.
[Adverse Reactions]
This product is well tolerated. Common adverse reactions include diarrhea, headache, nausea, abdominal pain, gastrointestinal bloating, and constipation. Occasionally, elevated serum aminotransferases (ALT, AST), rash, dizziness, drowsiness, and insomnia may occur. These adverse reactions are generally mild and resolve spontaneously, unrelated to dosage.
[Contraindications]
This product is contraindicated in patients with allergies, severe renal impairment, and infants.
[Precautions]
1. Do not use for more than 7 days. If symptoms persist or disappear, consult a physician or pharmacist. 2. Do not use again within two months. If symptoms recur, seek medical attention immediately. 3. Do not use this product if: swallowing is difficult or painful; vomiting blood; or if you have bloody or black stools. These may be signs of a serious condition; consult a physician. 4. Patients with liver dysfunction or abnormal blood counts should use this product under the guidance of a physician. 5. If heartburn persists or worsens, discontinue use and seek medical attention. 6. Children should only use this product under the guidance of a physician. 7. Use with caution during pregnancy or lactation. 8. In case of overdose or serious adverse reactions, seek medical attention immediately. 9. Contraindicated if allergic to this product; use with caution if allergic. 10. Do not use if the properties of this product change. 11. Keep this product out of reach of children. 12. Children must be supervised by an adult before use. 13. If you are using other medications, consult a physician or pharmacist before using this product.
[Special Use]
Children's Precautions: Contraindicated for use in infants and young children.
Precautions During Pregnancy and Lactation: Use with caution during pregnancy and lactation.
Precautions for Elderly Patients: This study has not been conducted and no reliable references are available.
[Drug Interactions]
1. Avoid concomitant use with oral imidazole antifungals such as ketoconazole, itraconazole, miconazole, and fluconazole. 2. Concomitant use of omeprazole and clarithromycin may increase the incidence of central nervous system (primarily headache) and gastrointestinal adverse reactions. 3. Avoid concomitant use with diazepam (Valium), phenytoin, warfarin, nifedipine, digoxin, cisapride, quinidine, cyclosporine, caffeine, and theophylline. 4. Concomitant use with other medications may cause drug interactions. Consult your physician or pharmacist for details.
[Pharmacological Actions]
Proton pump inhibitors. This drug is a fat-soluble, weakly alkaline drug that tends to concentrate in acidic environments. Therefore, after oral administration, it is specifically distributed in the secretory tubules of the gastric parietal cells. In this highly acidic environment, it is converted to its active form, the sulfenamide. This form then irreversibly binds to the sulfhydryl group of the H+, K+-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells via a disulfide bond, forming a sulfenamide-proton pump complex. This inhibits the enzyme's activity and blocks the final step in gastric acid secretion. Therefore, this drug has a strong and long-lasting inhibitory effect on gastric acid secretion caused by various causes.
[Storage]
Store in a dry, airtight container protected from light.
[Strength]
10mg
[Packaging]
10mg*28s/box
[Expiry Period]
24 months
[Approval Number]
National Medicine Standard No. H20044871
[Manufacturer]
Company Name: Shandong Xinshidai Pharmaceutical Co., Ltd.
