Product Overview
[Drug Name]
Generic Name: Nicergoline Tablets
Trade Name: Fulutong
English Name: Nicergoline Tablets
Chinese Pinyin: Nimaijiaolin Pian
[Ingredients]
Main Ingredient: The main ingredient of this product is nicergoline, whose chemical name is 10α-methoxy-1,6-dimethylergoline-8β-carbinol-5-bromonicotinate.
[Properties]
This product is a sugar-coated tablet that appears white or off-white after removal of the sugar coating.
[Indications]
1. Improves low motivation and affective disorders (slowed reaction time, poor concentration, memory loss, lack of motivation, depression, restlessness, etc.) caused by cerebral arteriosclerosis and sequelae of stroke. 2. Acute and chronic peripheral circulatory disorders (limb vascular occlusive disease, Raynaud's syndrome, and other symptoms of peripheral circulatory impairment). It is also suitable for vascular dementia, especially in the early stages of treatment, where it can improve cognition and memory and reduce the severity of the disease.
[Dosage and Administration]
Oral administration, do not chew. 20-60 mg (2-6 tablets) daily, divided into 2-3 doses. Continue administration for a sufficient period of at least six months. Continued use is at the discretion of the physician.
[Adverse Reactions]
No serious adverse reactions have been reported. Hypotension, dizziness, stomach pain, hot flashes, facial flushing, drowsiness, and insomnia may occur. In clinical trials, elevated blood uric acid concentrations were observed, but this phenomenon was not correlated with the dose or duration of administration.
[Contraindications]
This product is not suitable for the following conditions: recent myocardial infarction, acute hemorrhage, severe bradycardia, orthostatic dysregulation, bleeding tendency, and hypersensitivity to nicergoline.
[Precautions]
1. Use only under the guidance of a physician. 2. This product generally has no effect on blood pressure at therapeutic doses, but may gradually lower blood pressure in sensitive patients. 3. Use with caution in patients with hyperuricemia or a history of gout. 4. The dose should be reduced in patients with renal insufficiency. 5. Pregnant women should generally avoid using this medication. If necessary, consider the risks and benefits. 6. Avoid alcohol consumption while taking this medication. Keep out of reach of children.
[Special Use]
Precautions for Children:
Based on the current indication, this medication is not for use in children.
Precautions for Pregnancy and Lactation:
Toxicity studies have failed to demonstrate teratogenicity with nicergoline. Based on its indication, this medication is not for use in pregnant or lactating women.
Precautions for Elderly Patients:
Pharmacokinetic and tolerability studies have shown no difference in dosage and administration between adults and the elderly.
[Drug Interactions]
Nicergoline tablets may enhance the effects of antihypertensive drugs. Since nicergoline is metabolized via CYTP450 2D6, interactions with drugs that share the same metabolic pathway cannot be ruled out.
[Pharmacological Actions]
This product is a semi-synthetic ergot alkaloid derivative. It exhibits α-receptor blocking and vasodilatory properties. It may enhance brain cell energy metabolism and increase oxygen and glucose utilization. This product is a semi-synthetic ergot alkaloid derivative. It has alpha-receptor blocking and vasodilatory properties. It can enhance brain cell energy metabolism and increase oxygen and glucose utilization. It promotes the conversion of the neurotransmitter dopamine, increasing nerve conduction, enhancing brain protein synthesis, and improving brain function.
Storage: Protect from light and store in a sealed container.
Specifications: 10 mg
Packaging: 36 tablets/box.
Expiry Period: 24 months.
Approval Number: National Medicine Standard H10980103
Manufacturer: Hainan Zanbang Pharmaceutical Co., Ltd.
