Product Overview
【Drug Name】
Generic Name: Mecobalamin Tablets
Brand Name: Daifang
English Name: Mecobalamin Tablets
Pinyin: Jiagu, an Pian
【Ingredients】
The main ingredient of this product is mecobalamin, its chemical name is: Co-[-(5,6-dimethylbenzimidazolyl)]-Co-methylcobalaminamide.
【Appearance】
This product is a film-coated tablet. After removing the coating, the tablet core is light red.
【Indications】
Peripheral neuropathy.
【Dosage and Administration】
Oral administration. The usual adult dose is 0.5 mg three times a day, which may be increased or decreased according to age and symptoms.
【Adverse Reactions】
1. Allergy: Occasionally, a rash may occur (incidence rate 0.1%). If this occurs, discontinue use.
2. Other: Occasionally (incidence rate 5%–0.1%), loss of appetite, nausea, vomiting, and diarrhea may occur.
【Contraindications】
Contraindicated in patients with a history of allergy to mecobalamin or any of the excipients in the prescription.
【Precautions】
1. If ineffective after one month of use, discontinue use.
2. Workers exposed to mercury and its compounds should not take this product in large quantities or for extended periods.
3. Once opened, store this product away from light and moisture.
【Special Populations】
Children: Follow doctor's instructions.
Pregnancy and Lactation: Although methylcobalamin has not shown teratogenic effects in animal studies, its safety in pregnant women is unclear. It is unclear whether methylcobalamin is excreted in breast milk, but animal studies have reported its excretion in breast milk. The safety of this product in lactating women is unclear.
Elderly: Due to decreased function in the elderly, it is recommended to reduce the dosage appropriately under the guidance of a doctor.
【Drug Interactions】
Not yet clear.
【Pharmacological Action】
This product is an endogenous coenzyme B12 that participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction of homocysteine to methionine. Animal experiments have shown that this product enters neuronal organelles more easily than cyanocobalamin, participating in the synthesis of thymidine in brain cells and spinal cord neurons, promoting folic acid utilization and nucleic acid metabolism, and its effect on promoting nucleic acid and protein synthesis is stronger than that of cyanocobalamin. This product can promote axonal transport function and axonal regeneration, normalize the transport of sciatic nerve axonal skeletal proteins induced by streptozotocin in diabetic rats, and inhibit drug-induced neurodegeneration, such as that induced by doxorubicin, acrylamide, vincristine, and neurological diseases in spontaneously hypertensive rats. In rat tissue culture, this product has been found to promote lecithin...
【Storage】
Protect from light, seal tightly
【Specification】
0.5mg
【Packaging Specification】
0.5mg*16 tablets/box
【Shelf Life】
24 months
【Approval Number】
National Drug Approval Number H20051425
【Manufacturer】
Company Name: Chenxin Pharmaceutical Co., Ltd.
